stc
Brian Sykes Lab

Version: 6.0.2 - Sep / 2011
Download and Installation

Purpose: Stc - Structural Thermodynamics Calculations
A program which performs free energy calculations from the structure of different complexes.

Table of Contents

  1. Introduction

  2. Using the Software

Overview


References, Acknowledgements, and Copyright


Download and Installation

  1. This software is a self contained tcl/tk starkit which should make installation fairly trivial. See the Release notes for the latest updates. Download the software appropriate for your machine:

  2. Double click the download file. You should now get a new file on the desktop (or your download directory) represented by the stc icon. For macosx, you may want to drag the stc icon into /Applications or keep it on your desktop.

  3. Now let's make sure the software is working. Download data and examples (11MB) and double click (or un-tar) this file to create the stc-6.0-x-examples folder. (see the examples.readme file for a quick summary of each example provided).

  4. To run an example, double click on the stc.command file.

Setup your Data

  1. Create a working directory.
  2. Copy structure files here (pdb format).

  3. (optional) Create an stc.defaults file to customize how this software runs.
  4. (optional) Copy a custom residue library here.
  5. (optional) Copy each custom ASA file here.
  6. (optional) Copy each custom sconf file here.
The data and examples file contain many examples demonstrating the input above.

The Initial STC window


The Calc ASA window


The Thermodynamics Window


Output - Basic results


Output - Verbose results


Output - histograms


Multiple Structures


Multiple Structure Scripts


Troubleshooting


Back to stc home

This file last updated:

Questions to: bionmrwebmaster@biochem.ualberta.ca