Sykes NMR Wiki

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Welcome to our lab in the Department of Biochemistry in the Faculty of Medicine at the University of Alberta.
We study of the structure, dynamics and function of proteins, especially those that make up the thin filament of cardiac muscle and regulate contraction.
Structural biology, using nuclear magnetic resonance spectroscopy, is the primary tool in our research.
One recent focus has been the discovery and development of calcium sensitizers as potential drugs.

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The structure of a calcium sensitizing compound bound to the Troponin-C Troponin-I complex which regulates muscle contraction.


Brian Sykes' group, April 2014 (see Personnel and Pictures of the group)

Links

Publications PubMed (Sykes BD)
Dept of Biochem last 12 months
PDB Protein Data Bank
NANUC National NMR Centre
SpinSights Agilent NMR


Recent News

*August/13 Updated group picture


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